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Covering the wound with a waterproof bandage is crucial for ensuring safe food handling. This approach not only protects the wound from bacteria and other contaminants that may be present in the kitchen environment, but it also prevents any bodily fluids from coming into contact with food, utensils, or surfaces. A waterproof bandage effectively keeps the wound secure and minimizes the risk of cross-contamination, ensuring that food safety protocols are maintained.

Other options, such as wearing multiple layers of bandages, may not provide the same level of protection, as they can become loose or dislodged and might still allow the wound to be exposed or infected. Sanitizing the wound frequently is not practical or effective in a food handling context, and keeping the wound exposed to the air poses a clear risk of contamination. Thus, using a waterproof bandage is the best practice for a food handler with an infected hand wound.